Nick Alden Visiting Assistant Professor of Chemistry

Science Addition A329
540-458-4868
nalden@wlu.edu
Curriculum Vitae

Education

Pennsylvania State University, University Park, Pennsylvania 2019-2023
Ph.D. Bioengineering
University Fellow 2019-2020
Diefenderfer Fellow 2022-2023

Virginia Tech University, Blacksburg, Virginia 2013-2018
M.S. Mechanical Engineering with Biomedical Engineering option, May 2018
B.S. Mechanical Engineering, minor in Biomedical Engineering, May 2017
Pi Tau Sigma National Mechanical Engineering Honor Society 2017; Sigma Alpha Lambda National Leadership and Honors Organization 2015-2017; Tau Sigma National Honor Society 2014-17;
National Society of Collegiate Scholars 2014-17

West Virginia University, Morgantown, West Virginia, 2012-2013
Major: General Engineering
Phi Sigma Theta National Honor Society 2012-13

Selected Publications

Under Review
Nick A. Alden, Tyus Yeingst, Hanna M. Pfeiffer, Nazmiye Celik, Julien H. Arrizabalaga, Angelica M. Helton, Yiming Liu, Douglas B. Stairs, Adam B. Glick, Neerav Goyal, & Daniel J. Hayes; Near-Infrared Plasmonic Nanoparticles Deliver miRNA-34a Mimics Causing Esophageal Cancer Cell Apoptosis In Vivo; Advanced Healthcare Materials, 2023.

Nick Alden, Julien Arrizabalaga, Yiming Liu, Shantu Amin, Krishne Gowda, Shun Yao, Marco Archetti, Adam Glick, Daniel Hayes (2022). Delivery of Therapeutic miR-148b Mimics via Poly(Beta Amino Ester) Polyplexes for the Treatment of Non-Small Cell Lung Cancer

Published
Nick Alden, Julien Arrizabalaga, Yiming Liu, Shantu Amin, Krishne Gowda, Shun Yao, Marco Archetti, Adam Glick, Daniel Hayes; Delivery of Therapeutic miR-148b Mimics via Poly(Beta Amino Ester) Polyplexes for the Treatment of Non-Small Cell Lung Cancer; ACS Lanmuir, 2022

Nick A. Alden, A.Cameron Varano, William J. Dearnaley, Maria J. Solares, William Y. Luqiu, Yanping Liang, Zhi Sheng, Sarah M. McDonald, John Damiano, Jennifer McConnell, Madeline J. Dukes, and Deborah F. Kelly (2019). Cryo-EM-on-a-Chip: Custom-designed Substrates for the 3D Analysis of Macromolecules. Small. 15(21), 1900918.

William J. Dearnaley, Beatrice Schleupner, A.Cameron Varano, Nick A. Alden, Floricel Gonzalez, Michael Casasanta, Birgit E. Scharf, Madeline J. Dukes and Deborah F. Kelly (2019). Liquid-Cell Electron Tomography of Biological Systems. Nano Letters (in press) DOI: 10.1021/acs.nanolett.9b01309.

A.Cameron Varano, Nick A. Alden, William J. Dearnaley, Michael Casasanta, John Damiano, Jennifer McConnell, Madeline J. Dukes, and Deborah F. Kelly (2019). Customizable Cryo-EM Chips Improve 3D Analysis of Macromolecules. Microscopy & Microanalysis. (25) S2, 1310-1311.

Yanping Liang, William J. Dearnaley, Nick A. Alden, Maria J. Solares, Kevin J. Pridham, A.Cameron Varano, Zhi Sheng, Elizabeth All, and Deborah F. Kelly (2019). Correcting Errors in the BRCA1 Warning System. DNA Repair. 73, 120 – 128.

Yanping Liang, William Dearnaley, A. Cameron Varano, Carly E. Winton, Brian L. Gilmore, Nick Alden, Zhi Sheng, and Deborah F. Kelly (2017). Structural Analysis of BRCA1 Reveals Modification Hot Spot. Science Advances. 3:e1701386.